Journal
JOURNAL OF CONTROLLED RELEASE
Volume 205, Issue -, Pages 45-57Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jconrel.2014.11.030
Keywords
RDRP; ATRP; RAFT; Bioconjugates; Biohybrids; Polymer
Funding
- NSF [DMR 09-69301, CHE 10-26060]
- CRP Consortium
- Division Of Materials Research
- Direct For Mathematical & Physical Scien [969301] Funding Source: National Science Foundation
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The use of reversible deactivation radical polymerization (RDRP) methods has significantly expanded the field of bioconjugate synthesis. RDRP procedures have allowed the preparation of a broad range of functional materials that could not be realized using prior art poly(ethylene glycol) functionalization. The review of procedures for synthesis of biomaterials is presented with a special focus on the use of RDRP to prepare biohybrids with proteins, DNA and RNA. (C) 2014 Elsevier B.V. All rights reserved.
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