Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 165, Issue 1, Pages 208-222Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1476-5381.2011.01540.x
Keywords
RAMP2; CGRP8-37; intermedin; Rac1; thrombin
Categories
Funding
- Excellence Cluster Cardiopulmonary System postdoc grant
- University of Giessen Anschubfinanzierung
- Deutsche Forschungsgemeinschaft [SFB 547, Graduiertenkolleg 534]
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BACKGROUND AND PURPOSE Intermedin is a member of the calcitonin gene-related-peptide (CGRP) family expressed in endothelial cells and acts via calcitonin receptor-like receptors (CLRs). Here we have analysed the receptors for intermedin and its effect on the endothelial barrier in monolayers of human umbilical vein endothelial cells (HUVECs).
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