Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 164, Issue 8, Pages 1990-2002Publisher
WILEY
DOI: 10.1111/j.1476-5381.2011.01501.x
Keywords
adipocyte-derived relaxing factor; catalase; hydrogen peroxide; ion channels; mouse; PAR2; perivascular adipose tissue; potassium channels; protease-activated receptors; proteinase-activated receptors; relaxation
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Funding
- Canadian Institutes for Health Research
- Qatar Foundation [08 165-3-054]
- Heart and Stroke Foundation of Alberta
- Heart and Stroke Foundation of Nunavut
- Canadian Diabetes Association
- Alberta Cancer Board
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BACKGROUND AND PURPOSE We hypothesized that proteinase-activated receptor-2 (PAR2)-mediated vasorelaxation in murine aorta tissue can be due in part to the release of adipocyte-derived relaxing factors (ADRFs).
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