Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 159, Issue 5, Pages 1039-1050Publisher
WILEY
DOI: 10.1111/j.1476-5381.2009.00603.x
Keywords
calcium-sensing receptor; class C GPCR; Venus Fly Trap domain; cysteine-rich domain; dimerization; heptahelical domain
Categories
Funding
- Australian Research Council
- National Health and Medical Research Council of Australia
Ask authors/readers for more resources
In this article we consider the molecular basis of sensing and signalling by the extracellular calcium-sensing receptor. We consider the nature of its ligands and sensing modalities, the identities of its major protein domains and their roles in sensing, signalling and trafficking as well as the significance of receptor homo-and hetero-dimerization. Finally, we consider the current, incomplete, state of knowledge regarding the requirements for ligand-specific signalling. British Journal of Pharmacology (2010) 159, 1039-1050; doi: 10.1111/j.1476-5381.2009.00603.x; published online 5 February 2010
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
