Related references
Note: Only part of the references are listed.Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides
Yuzhe Du et al.
BIOCHEMICAL JOURNAL (2009)
Structure of the Analgesic μ-Conotoxin KIIIA and Effects on the Structure and Function of Disulfide Deletion
Keith K. Khoo et al.
BIOCHEMISTRY (2009)
Early- and late-onset inherited erythromelalgia: genotypephenotype correlation
Chongyang Han et al.
BRAIN (2009)
Voltage-gated sodium channels in pain states: Role in pathophysiology and targets for treatment
Sulayman D. Dib-Hajj et al.
BRAIN RESEARCH REVIEWS (2009)
First mutation in the voltage-gated NaV1.1 subunit gene SCN1A with co-occurring familial hemiplegic migraine and epilepsy
M-J Castro et al.
CEPHALALGIA (2009)
Structural Determinants of Drugs Acting on the Nav1.8 Channel
Liam E. Browne et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The ataxia3 Mutation in the N-Terminal Cytoplasmic Domain of Sodium Channel Nav1.6 Disrupts Intracellular Trafficking
Lisa M. Sharkey et al.
JOURNAL OF NEUROSCIENCE (2009)
Primary erythermalgia as a sodium channelopathy - Screening for SCN9A mutations: Exclusion of a causal role of SCN10A and SCN11A
Joost P. H. Drenth et al.
ARCHIVES OF DERMATOLOGY (2008)
Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels NaV1.2, 1.6 and 1.7
Brian Fiedler et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Tetrameric bacterial sodium channels: Characterization of structure, stability, and drug binding
Ghasem Nurani et al.
BIOCHEMISTRY (2008)
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain
Irene Drizin et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Imidazopyridines:: A novel class of hNav1.7 channel blockers
Clare London et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Models of the structure and gating mechanisms of the pore domain of the NaChBac ion channel
Yinon Shafrir et al.
BIOPHYSICAL JOURNAL (2008)
Models of voltage-dependent conformational changes in NaChBac channels
Yinon Shafrir et al.
BIOPHYSICAL JOURNAL (2008)
How do mutant Nav1.1 sodium channels cause epilepsy?
David S. Ragsdale
BRAIN RESEARCH REVIEWS (2008)
Guide to receptors and channels (GRAC), 3rd edition
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Impaired NaV1.2 function and reduced cell surface expression in benign familial neonatal-infantile seizures
Sunita N. Misra et al.
EPILEPSIA (2008)
Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain II voltage sensor in the closed configuration
Yucheng Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain
Michael E. Kort et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Inherited Neuronal Ion Channelopathies: New Windows on Complex Neurological Diseases
William A. Catterall et al.
JOURNAL OF NEUROSCIENCE (2008)
Paroxysmal extreme pain disorder mutations within the D3/S4-S5 linker of Nav1.7 cause moderate destabilization of fast inactivation
Brian W. Jarecki et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Mutation I136V alters electrophysiological properties of the NaV1.7 channel in a family with onset of erythromelalgia in the second decade
Xiaoyang Cheng et al.
MOLECULAR PAIN (2008)
ProTx-II, a Selective Inhibitor of Nav1.7 Sodium Channels, Blocks Action Potential Propagation in Nociceptors
William A. Schmalhofer et al.
MOLECULAR PHARMACOLOGY (2008)
Structure of a β1-adrenergic G-protein-coupled receptor
Tony Warne et al.
NATURE (2008)
Reduced expression of Nav 1.6 sodium channels and compensation by Nav 1.2 channels in mice heterozygous for a null mutation in Scn8a
Ana V. Vega et al.
NEUROSCIENCE LETTERS (2008)
Tetrodotoxin - A brief history
Toshio Narahashi
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2008)
SCN5A channelopathies - An update on mutations and mechanisms
Thomas Zimmer et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2008)
Trafficking and cellular distribution of voltage-gated sodium channels
Fiona S. Cusdin et al.
TRAFFIC (2008)
Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7
Brande S. Williams et al.
BIOCHEMISTRY (2007)
High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor
Vadim Cherezov et al.
SCIENCE (2007)
Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment
Stephen B. Long et al.
NATURE (2007)
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
Soren G. F. Rasmussen et al.
NATURE (2007)
Docking of μ-conotoxin GIIIA in the sodium channel outer vestibule
Gaurav Choudhary et al.
CHANNELS (2007)
Paroxysmal extreme pain disorder (previously familial rectal pain syndrome)
C. R. Fertleman et al.
NEUROLOGY (2007)
The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Nav1.6 voltage-dependent sodium channel
Christian Rosker et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons:: A circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation
Ikuo Ogiwara et al.
JOURNAL OF NEUROSCIENCE (2007)
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat
Michael F. Jarvis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Sodium channel blockade may contribute to the analgesic efficacy of antidepressants
Ivy E. Dick et al.
JOURNAL OF PAIN (2007)
Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations
Y. P. Goldberg et al.
CLINICAL GENETICS (2007)
Insect-selective spider toxins targeting voltage-gated sodium-channels
Graham M. Nicholson
TOXICON (2007)
Isolation and structure-activity of μ-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels
Richard J. Lewis et al.
MOLECULAR PHARMACOLOGY (2007)
Polarized distribution of ion channels within microdomains of the axon initial segment
Audra Van Wart et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2007)
Sodium channel auxiliary subunits
Tsai-Tien Tseng et al.
JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY (2007)
Solution structure and functional characterization of Jingzhaotoxin-XI: A novel gating modifier of both potassium and sodium channels
Zhi Liao et al.
BIOCHEMISTRY (2006)
An SCN9A channelopathy causes congenital inability to experience pain
James J. Cox et al.
NATURE (2006)
SCN9A mutations in paroxysmal extreme pain disorder:: Allelic variants underlie distinct channel defects and phenotypes
Caroline R. Fertleman et al.
NEURON (2006)
μO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits
J. Ekberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice
Mohammed A. Nassar et al.
MOLECULAR PAIN (2006)
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy
Frank H. Yu et al.
NATURE NEUROSCIENCE (2006)
The distribution and targeting of neuronal voltage-gated ion channels
Helen C. Lai et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Brugada electrocardiographic pattern due to tricyclic antidepressant overdose
M Akhtar et al.
JOURNAL OF ELECTROCARDIOLOGY (2006)
Heterozygosity for a protein truncation mutation of sodium channel SCN8A in a patient with cerebellar atrophy, ataxia, and mental retardation
M. M. Trudeau et al.
JOURNAL OF MEDICAL GENETICS (2006)
Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes
F Bosmans et al.
MOLECULAR PHARMACOLOGY (2006)
The primary periodic paralyses: diagnosis, pathogenesis and treatment
SL Venance et al.
BRAIN (2006)
Genetic testing in the long QT syndrome - Development and validation of an efficient approach to genotyping in clinical practice
C Napolitano et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
WA Catterall et al.
PHARMACOLOGICAL REVIEWS (2005)
Neuropathic pain develops normally in mice lacking both Nav1.7 and Nav1.8
Mohammed A. Nassar et al.
MOLECULAR PAIN (2005)
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
SB Long et al.
SCIENCE (2005)
Sodium channel mutations in epilepsy and other neurological disorders
MH Meisler et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Contribution of the tetrodotoxin-resistant voltage-gated sodium channel Nav1.9 to sensory transmission and nociceptive behavior
BT Priest et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mechanism of local anesthetic drug action on voltage-gated sodium channels
HA Fozzard et al.
CURRENT PHARMACEUTICAL DESIGN (2005)
A gating hinge in Na+ channels:: A molecular switch for electrical signaling
Y Zhao et al.
NEURON (2004)
Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy
TR Cummins et al.
JOURNAL OF NEUROSCIENCE (2004)
Interactions of local anesthetics with voltage-gated Na+ channels
C Nau et al.
JOURNAL OF MEMBRANE BIOLOGY (2004)
Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain
MA Nassar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Binding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady-state activation
NB Cronin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Genetic control of sodium channel function
HL Tan et al.
CARDIOVASCULAR RESEARCH (2003)
Mutations of sodium channel α subunit type 1 (SCN1A) in intractable childhood epilepsies with frequent generalized tonic-clonic seizures
T Fujiwara et al.
BRAIN (2003)
Overdose of cyclic antidepressants and the Brugada syndrome
D Goldgran-Toledano et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Critical molecular determinants of voltage-gated sodium channel sensitivity to μ-conotoxins GIIIA/B
TR Cummins et al.
MOLECULAR PHARMACOLOGY (2002)
A prokaryotic voltage-gated sodium channel
DJ Ren et al.
SCIENCE (2001)
Interictal spikes in focal epileptogenesis
M de Curtis et al.
PROGRESS IN NEUROBIOLOGY (2001)
The voltage-sensitive sodium channel is a bell-shaped molecule with several cavities
C Sato et al.
NATURE (2001)
Transient ST segment elevation in right precordial leads induced by psychotropic drugs: Relationship to the Brugada syndrome
F Rouleau et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2001)
Spectrum of sodium channel disturbances in the nondystrophic myotonias and periodic paralyses
SC Cannon
KIDNEY INTERNATIONAL (2000)
Share Paper
