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Blocking receptors on the inside: pepducin-based intervention of PAR signaling and thrombosis
A Kuliopulos et al.
LIFE SCIENCES (2003)
Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells
R Colognato et al.
BLOOD (2003)
PAR-2 activation, PGE2, and COX-2 in human asthmatic and nonasthmatic airway smooth muscle cells
LS Chambers et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)
Modulation by cAMP of IL-1β-induced eotaxin and MCP-1 expression and release in human airway smooth muscle cells
WA Wuyts et al.
EUROPEAN RESPIRATORY JOURNAL (2003)
Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration
EA Goncharova et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2003)
Protease-activated receptor-2 signaling triggers dendritic cell development
RC Fields et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Accentuated T helper type 2 airway response after allergen challenge in cyclooxygenase-1-/- but not cyclooxygenase-2-/- mice
MA Carey et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2003)
Receptors and pathways mediating the effects of prostaglandin E2 on airway tone
SL Tilley et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)
Protease-activated receptor (PAR)-independent growth and pro-inflammatory actions of thrombin on human cultured airway smooth muscle
T Tran et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2
BB Moore et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)
Prostaglandin E2 inhibits production of the inflammatory chemokines CCL3 and CCL4 in dendritic cells
H Jing et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2003)
Prostaglandin E-2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation
JE Kolodsick et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2003)
Cockroach proteases increase IL-8 expression in human bronchial epithelial cells via activation of protease-activated receptor (PAR)-2 and extracellular-signal-regulated kinase
K Page et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2003)
Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells
H Kataoka et al.
BLOOD (2003)
Role of lipopolysaccharide (LPS) in asthma and other pulmonary conditions
O Michel
JOURNAL OF ENDOTOXIN RESEARCH (2003)
Thrombin enhancement of interleukin-1 expression in mononuclear cells: Involvement of proteinase-activated receptor-1
A Naldini et al.
CYTOKINE (2002)
The lineage decisions of helper T cells
KM Murphy et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Prostaglandin E2 synthesis and suppression of fibroblast proliferation by alveolar epithelial cells is cyclooxygenase-2-dependent
V Lama et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
A key role for prostaglandin I2 in limiting lung mucosal Th2, but not Th1, responses to inhaled allergen
Z Jaffar et al.
JOURNAL OF IMMUNOLOGY (2002)
Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway
F Schmidlin et al.
JOURNAL OF IMMUNOLOGY (2002)
Augmentation of allergic inflammation in prostanoid IP receptor deficient mice
Y Takahashi et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
The immunomodulatory actions of prostaglandin E2 on allergic airway responses in the rat
JG Martin et al.
JOURNAL OF IMMUNOLOGY (2002)
PGE2 sensitizes cultured pulmonary vagal sensory neurons to chemical and electrical stimuli
K Kwong et al.
JOURNAL OF APPLIED PHYSIOLOGY (2002)
Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
L Covic et al.
NATURE MEDICINE (2002)
Influence of lipopolysaccharide exposure on airway function and allergic responses in developing mice
JR Cochran et al.
PEDIATRIC PULMONOLOGY (2002)
Thiazolidinediones as a novel class of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
H Cho et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)
Tryptase activates the mitogen-activated protein kinase/activator protein-1 pathway in human peripheral blood eosinophils, causing cytokine production and release
V Temkin et al.
JOURNAL OF IMMUNOLOGY (2002)
Role of protease-activated receptors in airway function: a target for therapeutic intervention?
RS Lan et al.
PHARMACOLOGY & THERAPEUTICS (2002)
Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis
JC Bonner et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Activation of endothelial cell protease activated receptor 1 by the protein C pathway
M Riewald et al.
SCIENCE (2002)
Protease-activated receptor-2 activating peptide SLIGRL inhibits bacterial lipopolysaccharide-induced recruitment of polymorphonuclear leukocytes into the airways of mice
JD Moffatt et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
International Union of Pharmacology. XXVIII. Proteinase-activated receptors
MD Hollenberg et al.
PHARMACOLOGICAL REVIEWS (2002)
Airways inflammation and COPD - Epithelial-neutrophil interactions
CA Pettersen et al.
CHEST (2002)
Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
N Asokananthan et al.
JOURNAL OF IMMUNOLOGY (2002)
Role of thrombin and its major cellular receptor, protease-activated receptor-1, in pulmonary fibrosis
DC Howell et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2002)
Expression of protease activated receptor-2 (PAR-2) in central airways of smokers and non-smokers
D Miotto et al.
THORAX (2002)
Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides
L Covic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
RANTES release by human airway smooth muscle:: effects of prostaglandin E2 and fenoterol
N Lazzeri et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2
S Miike et al.
JOURNAL OF IMMUNOLOGY (2001)
Thrombin differentiates normal lung fibroblasts to a myofibroblast phenotype via the proteolytically activated receptor-1 and a protein kinase C-dependent pathway
GS Bogatkevich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma
DA Knight et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2001)
Protection from pulmonary fibrosis in the absence of CCR2 signaling
BB Moore et al.
JOURNAL OF IMMUNOLOGY (2001)
Prostaglandin E2 increases surfactant secretion via the EP1 receptor in rat alveolar type II cells
MAM Morsy et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Prostaglandin E2 activates the ciliary beat frequency of cultured human nasal mucosa via the second messenger cyclic adenosine monophosphate
BR Haxel et al.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY (2001)
Intratracheal administration of activated protein C inhibits bleomycin-induced lung fibrosis in the mouse
H Yasui et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2001)
Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-β in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice
CB Keerthisingam et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Prostaglandin E2 increases cyclic AMP and inhibits endothelin-1 production/secretion by guinea-pig tracheal epithelial cells through EP4 receptors
S Pelletier et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Advances in immunology - Asthma
WW Busse et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
TGF-β1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2)
F Strutz et al.
KIDNEY INTERNATIONAL (2001)
Role of PGE(2) in protease-activated receptor-1,-2 and-4 mediated relaxation in the mouse isolated trachea
RS Lan et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Microbial lipopeptides induce the production of IL-17 in Th cells
C Infante-Duarte et al.
JOURNAL OF IMMUNOLOGY (2000)
Tumor necrosis factor-α-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells -: Modulation by cyclic adenosine monophosphate
AJ Ammit et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2000)
Effect of protease-activated receptor (PAR)-1, -2 and -4-activating peptides, thrombin and trypsin in rat isolated airways
JM Chow et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Inhibition of cellular action of thrombin by N3-cyclopropyl-7-{[4-(1-methylethyl)phenyl]methyl}-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist
HS Ahn et al.
BIOCHEMICAL PHARMACOLOGY (2000)
Proteolysis of the exodomain of recombinant protease-activated receptors: Prediction of receptor activation or inactivation by MALDI mass spectrometry
D Loew et al.
BIOCHEMISTRY (2000)
Prostaglandin E2 enhances chemical and mechanical sensitivities of pulmonary C fibers in the rat
CY Ho et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)
Prostaglandin E2 decreases allergen-stimulated release of prostaglandin D2 in airways of subjects with asthma
TV Hartert et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)
PAR3 is a cofactor for PAR4 activation by thrombin
M Nakanishi-Matsui et al.
NATURE (2000)
Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways
FLM Ricciardolo et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)
Modulation of airway smooth muscle tone by protease activated receptor-1,-2,-3 and-4 in trachea isolated from influenza A virus-infected mice
RS Lan et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Proteinase-activated receptor-2-mediated matrix metalloproteinase-9 release from airway epithelial cells
A Vliagoftis et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2000)