Journal
BRITISH JOURNAL OF OPHTHALMOLOGY
Volume 99, Issue 2, Pages 258-262Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/bjophthalmol-2013-304717
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Funding
- NEI NIH HHS [K08 EY022737] Funding Source: Medline
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Aim To evaluate outcomes of ab interno trabeculectomy (AIT) with the trabectome following failed trabeculectomy. Methods Prospective study of AITs and phaco-AITs after a failed trabeculectomy. The indication for AIT was intraocular pressure (IOP) above target on maximally tolerated therapy, and for phaco-AIT a visually significant cataract and need to lower IOP or glaucoma medications. Outcomes included IOP, medications, complications, secondary procedures and success, defined as IOP of less than 21 mm Hg and a greater than 20% reduction from baseline without further surgery. Exclusion criteria were trabeculectomy less than 3 months prior to AIT or follow-up under 1 year. Results Seventy-three eyes of 73 patients with 1 year follow-up were identified. At 1 year, mean IOP in AIT significantly decreased by 28% from 23.7 +/- 5.5 mm Hg, and medications from 2.8 +/- 1.2 to 2 +/- 1.3 (n=58). In phaco-AIT, the mean IOP decreased 19% from 20 +/- 5.9 mm Hg and medications from 2.5 +/- 1.5 to 1.6 +/- 1.4 (n=15). Transient hypotony occurred in 7%, and further surgery was necessary in 18%. For AIT and phaco-AIT, the 1-year cumulative probability of success was 81% and 87%, respectively. Conclusions Both AIT and phaco-AIT showed a reduction in IOP and medication use after 1 year, suggesting that AIT with or without cataract surgery is a safe and effective option following failed trabeculectomy.
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