Journal
BRITISH JOURNAL OF OPHTHALMOLOGY
Volume 98, Issue -, Pages 15-19Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/bjophthalmol-2013-304326
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Funding
- National Institutes of Health (Bethesda, Maryland, USA) [NIH R01-EY013178, P30-EY008098]
- Eye and Ear Foundation (Pittsburgh, Pennsylvania, USA)
- Research to Prevent Blindness (New York, New York, USA)
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Optical coherence tomography (OCT) is a commonly used imaging modality in the evaluation of glaucomatous damage. The commercially available spectral domain (SD)-OCT offers benefits in glaucoma assessment over the earlier generation of time domain-OCT due to increased axial resolution, faster scanning speeds and has been reported to have improved reproducibility but similar diagnostic accuracy. The capabilities of SD-OCT are rapidly advancing with 3D imaging, reproducible registration, and advanced segmentation algorithms of macular and optic nerve head regions. A review of the evidence to date suggests that retinal nerve fibre layer remains the dominant parameter for glaucoma diagnosis and detection of progression while initial studies of macular and optic nerve head parameters have shown promising results. SD-OCT still currently lacks the diagnostic performance for glaucoma screening.
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