Journal
BRITISH JOURNAL OF OPHTHALMOLOGY
Volume 93, Issue 5, Pages 634-637Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/bjo.2008.150276
Keywords
-
Categories
Funding
- NIH [R01 EY013516, P30 EY03040]
- Research to Prevent Blindness
Ask authors/readers for more resources
Aim: To measure total retinal blood flow in normal human eyes using Doppler Fourier-domain optical coherence tomography (FD-OCT). Methods: 10 normal people aged 35 to 69 years were measured for the right eye using Doppler FD-OCT. Double circular scans around the optic nerve heads were used. Four pairs of circular scans that transected all retinal branch vessels were completed in 2 s. Total retinal blood flow was obtained by summing the flows in the branch veins. Measurements from the eight scans were averaged. Veins with diameters > 33 mu m were taken into account. Results: Total retinal blood flow could be measured in eight of 10 subjects: mean (SD) = 45.6 (3.8) mu l/min (range 40.8 to 52.9 mu l/min). The coefficient of variation for repeated measurements was 10.5%. Measured vein diameters ranged from 33.3 to 155.4 mu m. The averaged flow speed was 19.3 (2.9) mm/s, which did not correlate with vessel diameter. There was no significant difference between flows in the superior and inferior retinal hemispheres. Conclusions: Double circular scanning using Doppler FD-OCT is a rapid and reproducible method to measure total retinal blood flow. These flow values are within the range previously established by laser Doppler flowmetry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available