Journal
BRITISH JOURNAL OF OPHTHALMOLOGY
Volume 93, Issue 1, Pages 66-72Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/bjo.2007.131722
Keywords
-
Categories
Funding
- Department for Employment and Learning in Northern Ireland
- NATIONAL EYE INSTITUTE [R01EY019470] Funding Source: NIH RePORTER
Ask authors/readers for more resources
Aim: Large variations in results of diagnostic tests for mild to moderate dry eye are widely recognised. The purpose of this study was to assess if there was concordance between common dry eye diagnostic tests. Methods: A total of 91 subjects were recruited to the study. The tear film and ocular surface were evaluated using the phenol red thread test (PRT), tear film break-up time (TBUT), biomicroscopic examination and impression cytological assessment of conjunctival goblet cells. Dry eye symptoms were assessed using McMonnies' dry eye questionnaire (MQ) and statistical correlations between all tests were assessed. Results: This study cohort did not include severe aqueous deficient dry eye patients as determined by the PRT. A statistically significant difference was noted between PRT results and all other tests (p <= 0.001). Only Meibomian gland pathology, MQ, reduced goblet cell density and TBUT (<= 7 s) demonstrated correlation determined by McNemar's test. Conclusion: A correlation was found only between tests assessing lipid/mucous deficiency (Meibomian gland evaluation, goblet cell density, TBUT and MQ).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available