Journal
BRITISH JOURNAL OF NUTRITION
Volume 103, Issue 2, Pages 243-248Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S000711450999153X
Keywords
n-3 PUFA; DHA; Cardiovascular health; Cardiac autonomic balance
Categories
Funding
- ARC [LP0561211]
- Bartlett Grain Ply Ltd
- Australian Pork Ltd
- Australian Research Council [LP0561211] Funding Source: Australian Research Council
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Heart rate (HR) variability and large arterial compliance can be improved using fish oils. DHA, a component of fish oil, has cardiovascular health benefits, but its effect oil HR variability (HRV) and arterial compliance is yet to be quantified. Sixty-seven overweight or obese adults (thirty-six males and thirty-one females; 53 (SEM 2) year; BMI 31.7 (SEM 1.1) kg/m(2)) were randomly allocated to consume either 6 g/d sunola oil (control; n 17), fish oil (260 mg DHA + 60 mg EPA per at doses of 2 g/d (n 16), 4 g/d (n 17) or 6 g/d (n 17). Blood pressure, HR and compliance of large and small arteries were measured while supine at baseline and after 12 weeks in all participants, and HRV was assessed in a subgroup of forty-six participants. There was no effect of fish oil on blood pressure, small artery compliance or HR. However, the low frequency:high frequency ratio of HRV decreased with increasing closes of fish oil (r - 0.34, P=0.02), while large artery compliance increased (r 0.34, P=0.006). Moreover, the changes in these biomarkers were significantly correlated (r -0.31, P=0.04) and may reflect fish oil-induced improvements in arterial function and cardiac autonomic regulation.
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