4.8 Article

Electrophilic Cyanate As a Recognition Motif for Reactive Sulfur Species: Selective Fluorescence Detection of H2S

Journal

ANALYTICAL CHEMISTRY
Volume 88, Issue 1, Pages 1039-1043

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.5b04163

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Funding

  1. IZTECH (Izmir Institute of Technology)

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An ESIPT-based fluorescent dye, 3-hydroxyflavone, is chemically masked with an electrophilic cyanate motif in order to construct a fluorescent probe for cellular sulfur species. This novel probe structure, displays an extremely fast, highly sensitive and selective '' turn-on '' type fluorescent response toward H2S. We have also documented its utility for imaging of H2S in the living cells.

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