Journal
BRITISH JOURNAL OF NUTRITION
Volume 101, Issue 8, Pages 1140-1144Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114508059369
Keywords
Polyphenols; Fatty acids; Antioxidants; Spatial memory; Learning
Categories
Funding
- California Walnut Commission (Sacramento, CA, USA)
Ask authors/readers for more resources
Aged rats show decrements in performance on motor and cognitive tasks that require the use of spatial learning and memory. Previously we have shown that these deficits can be reversed by the polyphenolics in fruits and vegetables. Walnuts, which contain the n-3 fatty acids alpha-linolenic acid and linoleic acid, are a dietary source of polyphenols, antioxidants and lipids. Thus, the present study examined the effects of walnut supplementation on motor and cognitive ability in aged rats. Fischer 344 rats, aged 19 months, were fed a control, or a 2, 6 or 9 % walnut diet for 8 weeks before motor and cognitive testing. Results for the motor testing showed that the 2 % walnut diet improved performance on rod walking, while the 6 % walnut diet improved performance on the medium plank walk; the higher dose of the 9 % walnut diet did not improve psychomotor performance and on the large plank actually impaired performance. All of the walnut diets improved working memory in the Morris water maze, although the 9 % diet showed impaired reference memory. These findings show for the first time that moderate dietary walnut supplementation can improve cognitive and motor performance in aged rats.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available