Journal
BRITISH JOURNAL OF HAEMATOLOGY
Volume 160, Issue 2, Pages 171-176Publisher
WILEY
DOI: 10.1111/bjh.12102
Keywords
Waldenstrom macroglobulinaemia; trials; residual disease
Categories
Ask authors/readers for more resources
This report represents a further update of the consensus panel criteria for the assessment of clinical response in patients with Waldenstrom macroglobulinaemia (WM). These criteria have been updated in light of further data demonstrating an improvement in categorical responses with new drug regimens as well as acknowledgement of the fact that such responses are predictive of overall outcome. A number of key changes are proposed but challenges do however remain and these include the variability in kinetics of immunoglobulin M (IgM) reduction with different treatment modalities and the apparent discrepancy between IgM and bone marrow/tissue response noted with some regimens. Planned sequential bone marrow assessments are encouraged in clinical trials.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available