Journal
BRITISH JOURNAL OF HAEMATOLOGY
Volume 156, Issue 2, Pages 173-185Publisher
WILEY
DOI: 10.1111/j.1365-2141.2011.08920.x
Keywords
Anaemia; haemoglobin; erythropoiesis; elderly; ageing
Categories
Funding
- Johns Hopkins University School of Medicine
- American Society for Hematology
- NIH [DK082722]
- Celgene Corporation
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Developed countries, such as the United Kingdom, are experiencing a change in demographics resulting in the largest proportion of adults over 65 years of age that our health systems have ever experienced. As such, haematologists must be prepared to evaluate and treat anaemia in a more complicated patient population, but sufficient evidence-based guidelines are lacking. Critical next steps that must be taken to ensure the best care of this population include the determination of appropriate haemoglobin concentrations for older adults in light of age, gender, race, and comorbidities; the development of interventional trials that address physical performance outcomes in addition to haemoglobin targets; and translational studies which address the molecular pathogenesis of anaemia in older adults with the most advanced scientific approaches.
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