Journal
BEHAVIOUR RESEARCH AND THERAPY
Volume 48, Issue 1, Pages 60-67Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.brat.2009.09.009
Keywords
Anorexia Nervosa; Anxiety; Body mass index
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Funding
- NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH066117, T32MH076694] Funding Source: NIH RePORTER
- Medical Research Council [G0801418B] Funding Source: researchfish
- NIMH NIH HHS [MH66117, T32 MH076694, R01 MH066117-01, T32 MH076694-01A1, R01 MH066117, T32MH076694-03] Funding Source: Medline
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Objective: Extremely low body mass index (BMI) values are associated with increased risk for death and poor long-term prognosis in individuals with anorexia nervosa (AN). The present study explores childhood personality characteristics that could be associated with the ability to attain an extremely low BMI. Methods: Participants were 326 women from the Genetics of Anorexia Nervosa (GAN) Study who completed the Structured Interview for Anorexia Nervosa and Bulimic Syndromes and whose mother completed the Child Behavioral Checklist and/or Revised Dimensions of Temperament Survey. Results: Children who were described as having greater fear or anxiety by their mothers attained lower BMIs during AN (p < 0.02). Path analysis in the CAN and a validation sample, Price Foundation Anorexia Nervosa Trios Study, confirmed the relation between early childhood anxiety, caloric restriction, qualitative food item restriction, excessive exercise, and low BMI. Path analysis also confirmed a relation between childhood anxiety and caloric restriction, which mediated the relation between childhood anxiety and low BMI in the GAN sample only. Conclusion: Fearful or anxious behavior as a child was associated with the attainment of low BMI in AN and childhood anxiety was associated with caloric restriction. Measures of anxiety and factors associated with anxiety-proneness in childhood may index children at risk for restrictive behaviors and extremely low BMIs in AN. (C) 2009 Elsevier Ltd. All rights reserved.
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