Journal
ANALYTICAL CHEMISTRY
Volume 87, Issue 13, Pages 6718-6723Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.5b00853
Keywords
-
Categories
Funding
- National Basic Research Program of China (973 Program) [2013CB934400, 2012CB932400]
- NSFC [61361160412, 31400860]
- Priority Academic Pro-gram Development of Jiangsu Higher Education Institutions (PAPD)
- Jiangsu Key Laboratory for Carbon-based Functional Materials Devices
Ask authors/readers for more resources
We herein introduce a kind of fluorescent silicon nanoparticles (SiNPs) bioprobes, that is, peptides-conjugated SiNPs, which simultaneously feature small sizes (<10 nm), biological functionality, and stable and strong fluorescence (photoluminescent quantum yield (PLQY): as well as favorable biocompatibility. Taking advantage of these merits, we further demonstrate such resultant SiNPs bioprobes are superbly suitable for real-time immunofluorescence imaging of cancer cells. Meanwhile, malignant tumor cells could be specifically destroyed by the peptides-conjugated SiNPs, suggesting potential promise of simultaneous detection and treatment of cancer cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available