Journal
BRITISH JOURNAL OF DERMATOLOGY
Volume 161, Issue 1, Pages 95-101Publisher
WILEY
DOI: 10.1111/j.1365-2133.2009.09157.x
Keywords
contact dermatitis; contact sensitization; cosmetics; fragrance sensitization; general population; public health
Categories
Funding
- Danish Board of Health
- Danish Environmental Protection Agency
- Copenhagen County Research Foundation
- Aase and Einar Danielsens Foundation
- Velux Foundation
- ALK-Abello A/S, Denmark
- Danish Scientific Research Council
Ask authors/readers for more resources
Background The prevalence of sensitization to fragrance mix (FM) I and Myroxylon pereirae (MP, balsam of Peru) has decreased in recent years among Danish women with dermatitis. Objectives This study investigated whether the decrease could be confirmed among women in the general population. Furthermore, it addressed the morbidity of FM I sensitization. Methods In 1990, 1998 and 2006, 4299 individuals aged 18-69 years (18-41 years only in 1998) completed a premailed questionnaire and were patch tested to FM I and MP. Data were analysed by logistic regression analyses and associations were expressed as odds ratios (ORs) with 95% confidence intervals (CIs). Results The prevalence of FM I and MP sensitization followed an inverted V-pattern among women aged 18-41 years (i.e. an increase from 1990 to 1998, followed by a decrease from 1998 to 2006). Logistic regression analyses showed that 'medical consultation due to cosmetic dermatitis' (OR 3.37, 95% CI 1.83-6.20) and 'cosmetic dermatitis within the past 12 months' (OR 3.53, CI 2.02-6.17) were significantly associated with sensitization to FM I. Conclusions In line with trends observed in Danish patients with dermatitis, our results supported a recent decrease in the prevalence of FM I and MP sensitization in Denmark. The study also showed that fragrance sensitization was associated with self-reported cosmetic dermatitis and use of health care related to cosmetic dermatitis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available