4.5 Review

How the Timing and Quality of Early Experiences Influence the Development of Brain Architecture

Journal

CHILD DEVELOPMENT
Volume 81, Issue 1, Pages 28-40

Publisher

WILEY
DOI: 10.1111/j.1467-8624.2009.01380.x

Keywords

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Funding

  1. EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [P30HD015052] Funding Source: NIH RePORTER
  2. NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH080759, R01MH078829] Funding Source: NIH RePORTER
  3. NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS034458, F31NS103445] Funding Source: NIH RePORTER
  4. NICHD NIH HHS [HD15052, P30 HD015052] Funding Source: Medline
  5. NIMH NIH HHS [R01 MH080759, R01 MH078829, MH078829, MH080759, R01 MH078829-13] Funding Source: Medline
  6. NINDS NIH HHS [NS03445, R01 NS034458-12, R01 NS034458] Funding Source: Medline

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Early life events can exert a powerful influence on both the pattern of brain architecture and behavioral development. In this study a conceptual framework is provided for considering how the structure of early experience gets under the skin. The study begins with a description of the genetic framework that lays the foundation for brain development, and then proceeds to the ways experience interacts with and modifies the structures and functions of the developing brain. Much of the attention is focused on early experience and sensitive periods, although it is made clear that later experience also plays an important role in maintaining and elaborating this early wiring diagram, which is critical to establishing a solid footing for development beyond the early years.

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