Journal
CHILD DEVELOPMENT
Volume 81, Issue 1, Pages 183-199Publisher
WILEY
DOI: 10.1111/j.1467-8624.2009.01388.x
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Funding
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT [R01HD040219] Funding Source: NIH RePORTER
- CIHR [MOP42536] Funding Source: Medline
- NICHD NIH HHS [R01 HD040219-04, R01HD40219, R01 HD040219-03, R01 HD040219-02, R01 HD040219-01, R01 HD040219] Funding Source: Medline
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The authors examined internalizing behavior problems at middle childhood, adolescence, and young adulthood and brain-based measures of stress vulnerability in 154 right-handed, nonimpaired young adults (M age = 23 years): 71 (30 males, 41 females) born at extremely low birth weight (ELBW; < 1,000 g) and 83 (35 males, 48 females) controls born at normal birth weight (NBW). Internalizing behavior problems increased from adolescence to young adulthood among ELBW individuals. ELBW adults exhibited greater relative right frontal electroencephalogram activity at rest and more concurrent internalizing behavior problems than NBW controls. Being born at ELBW may have subtle influences on brain-behavior relations even in survivors without major impairments and evidence of these influences may not emerge until young adulthood.
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