Related references
Note: Only part of the references are listed.Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR
David W. Schoppy et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines
A. Peasland et al.
BRITISH JOURNAL OF CANCER (2011)
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia
Fanny Bouquet et al.
JOURNAL OF CELL SCIENCE (2011)
Discovery of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Protein Kinase as Potential Anticancer Agents
Jean-Damien Charrier et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Molecular Imaging of Hypoxia
Satish K. Chitneni et al.
JOURNAL OF NUCLEAR MEDICINE (2011)
Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR
Philip M. Reaper et al.
NATURE CHEMICAL BIOLOGY (2011)
Hypoxia-driven cell motility reflects the interplay between JMY and HIF-1α
A. S. Coutts et al.
ONCOGENE (2011)
GENOMIC INSTABILITY IN CANCER Strategies to improve radiotherapy with targeted drugs
Adrian C. Begg et al.
NATURE REVIEWS CANCER (2011)
Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability
Isabel M. Pires et al.
CANCER RESEARCH (2010)
Low-Field Magnetic Resonance Imaging to Visualize Chronic and Cycling Hypoxia in Tumor-Bearing Mice
Hironobu Yasui et al.
CANCER RESEARCH (2010)
Contextual Synthetic Lethality of Cancer Cell Kill Based on the Tumor Microenvironment
Norman Chan et al.
CANCER RESEARCH (2010)
Combining ATR Suppression with Oncogenic Ras Synergistically Increases Genomic Instability, Causing Synthetic Lethality or Tumorigenesis in a Dosage-Dependent Manner
Oren Gilad et al.
CANCER RESEARCH (2010)
Targeting Hypoxic Cells through the DNA Damage Response
Monica Olcina et al.
CLINICAL CANCER RESEARCH (2010)
mTORC1 Signaling under Hypoxic Conditions Is Controlled by ATM-Dependent Phosphorylation of HIF-1α
Hakan Cam et al.
MOLECULAR CELL (2010)
An Essential Role of the HIF-1 alpha-c-Myc Axis in Malignant Progression
Young-Gun Yoo et al.
HYPOXIA AND CONSEQUENCES FROM MOLECULE TO MALADY (2009)
Bringing H2AX into the Angiogenesis Family
Erinn B. Rankin et al.
CANCER CELL (2009)
Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling
Naseer Qayum et al.
CANCER RESEARCH (2009)
The combined status of ATM and p53 link tumor development with therapeutic response
Hai Jiang et al.
GENES & DEVELOPMENT (2009)
Development of HIF-1 inhibitors for cancer therapy
Barbara Onnis et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
ATM Activation and Signaling under Hypoxic Conditions
Zuzana Bencokova et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
Yaroslava Ruzankina et al.
NATURE GENETICS (2009)
Histone H2AX is integral to hypoxia-driven neovascularization
Matina Economopoulou et al.
NATURE MEDICINE (2009)
Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response
Hiroshi Nishida et al.
NUCLEIC ACIDS RESEARCH (2009)
Somatic mutations affect key pathways in lung adenocarcinoma
Li Ding et al.
NATURE (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control
Deborah Wilsker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Hypoxia, DNA repair and genetic instability
Robert G. Bristow et al.
NATURE REVIEWS CANCER (2008)
Targeting hypoxia cell signaling for cancer therapy
Giovanni Melillo
CANCER AND METASTASIS REVIEWS (2007)
Expression patterns of the ATM gene in mammary tissues and their associations with breast cancer survival
Chuanzhong Ye et al.
CANCER (2007)
Human cancer cells require ATR for cell cycle progression following exposure to ionizing radiation
P. J. Hurley et al.
ONCOGENE (2007)
Loss of ataxia telangiectasia mutated- and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival
Deborah Wilsker et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Genome-wide analysis of p53 under hypoxic conditions
EM Hammond et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status
D Sprong et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2006)
Mechanisms of common fragile site instability
TW Glover et al.
HUMAN MOLECULAR GENETICS (2005)
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
RG Syljuåsen et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Inhibition of ATR leads to increased sensitivity to hypoxia/reoxygenation
EM Hammond et al.
CANCER RESEARCH (2004)
ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining
HY Wang et al.
CANCER RESEARCH (2004)
Expression of ATM protein and its relationship with p53 in pancreatic carcinoma with tissue array
GZ Yu et al.
PANCREAS (2004)
Ovarian cancer: Strategies for overcoming resistance to chemotherapy
R Agarwal et al.
NATURE REVIEWS CANCER (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
JM Sogo et al.
SCIENCE (2002)
Curing metastatic testicular cancer
LH Einhorn
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Hypoxia links ATR and p53 through replication arrest
EM Hammond et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation
P Nghiem et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Share Paper
