Journal
BRITISH JOURNAL OF CANCER
Volume 104, Issue 1, Pages 19-23Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6606014
Keywords
FKBP5; immunophilins; chemoresistance
Categories
Ask authors/readers for more resources
FK506 binding protein 51 (FKBP51, also called FKBP5) belongs to a family of immunophilins, FK506 binding proteins (FKBPs). Members of this family are targets for drugs such as rapamycin and cyclosporine. Although FKBP5 shares characteristics with other FKBPs, it also has unique features, especially its role in the regulation of multiple signalling pathways and in tumourigenesis and chemoresistance. In this review, we will focus on the recently discovered role of FKBP5 in cancer aetiology and response to antineoplastic therapy. British Journal of Cancer (2011) 104, 19-23. doi:10.1038/sj.bjc.6606014 www.bjcancer.com Published online 30 November 2010 (C) 2011 Cancer Research UK
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available