Related references
Note: Only part of the references are listed.Endothelial deletion of hypoxia-inducible factor-2α (HIF-2α) alters vascular function and tumor angiogenesis
Nicolas Skuli et al.
BLOOD (2009)
Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer
E. Korkeila et al.
BRITISH JOURNAL OF CANCER (2009)
Cross-talk between Tumor and Endothelial Cells Involving the Notch3-DII4 Interaction Marks Escape from Tumor Dormancy
Stefano Indraccolo et al.
CANCER RESEARCH (2009)
Assessment of microvessel density and carbonic anhydrase-9 (CA-9) expression in rectal cancer
S. Rasheed et al.
PATHOLOGY RESEARCH AND PRACTICE (2009)
Blocking neuropilin-2 function inhibits tumor cell metastasis
Maresa Caunt et al.
CANCER CELL (2008)
Response-independent survival benefit in metastatic colorectal cancer: A comparative analysis of N9741 and AVF2107
Axel Grothey et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Bevacizumab Beyond First Progression Is Associated With Prolonged Overall Survival in Metastatic Colorectal Cancer: Results From a Large Observational Cohort Study (BRiTE)
Axel Grothey et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Regulation of multiple angiogenic pathways by D114 and Notch in human umbilical vein endothelial cells
Laura S. Harrington et al.
MICROVASCULAR RESEARCH (2008)
Delta-like 4 notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo
Ji-Liang Li et al.
CANCER RESEARCH (2007)
Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice
Nina Korsisaari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth
Gavin Thurston et al.
NATURE REVIEWS CANCER (2007)
Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency
Mayka Sanchez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
Mats Hellstroem et al.
NATURE (2007)
Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
Qi Pan et al.
CANCER CELL (2007)
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
Irene Noguera-Troise et al.
NATURE (2006)
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
John Ridgway et al.
NATURE (2006)
Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment
Alexander R. A. Anderson et al.
CELL (2006)
Inhibiting vascular endothelial growth factor receptor-2 signaling reduces tumor burden in the ApcMin/+ mouse model of early intestinal cancer
R. A. Goodlad et al.
CARCINOGENESIS (2006)
Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer
Nilay S. Patel et al.
CLINICAL CANCER RESEARCH (2006)
Predicting benefit from anti-angiogenic agents in malignancy
Adrian M. Jubb et al.
NATURE REVIEWS CANCER (2006)
Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function
CK Williams et al.
BLOOD (2006)
Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizurnab in metastatic colorectal cancer
AM Jubb et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues
EJ Soilleux et al.
HISTOPATHOLOGY (2005)
The androgen receptor is significantly associated with vascular endothelial growth factor and hypoxia sensing via hypoxia-inducible factors HIF-1a, HIF-2a, and the prolyl hydroxylases in human prostate cancer
JL Boddy et al.
CLINICAL CANCER RESEARCH (2005)
Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
NS Patel et al.
CANCER RESEARCH (2005)
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
JH van Es et al.
NATURE (2005)
Global cancer statistics, 2002
DM Parkin et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2005)
Expression of vascular endothelial growth factor, hypoxia inducible factor 1α, and carbonic anhydrase IX in human tumours
AM Jubb et al.
JOURNAL OF CLINICAL PATHOLOGY (2004)
Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer
Y Mizukami et al.
CANCER RESEARCH (2004)
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
RJ Appelhoff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Prognostic impact of hypoxia-inducible factors 1α and 2α in colorectal cancer patients:: Correlation with tumor angiogenesis and cyclooxygenase-2 expression
H Yoshimura et al.
CLINICAL CANCER RESEARCH (2004)
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
H Hurwitz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Dosage-sensitive requirement for mouse D114 in artery development
A Duarte et al.
GENES & DEVELOPMENT (2004)
Hypoxia up-regulates prolyl hydroxylase activity - A feedback mechansim that limits HIF-1 responses during reoxygenation
G D'Angelo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization
AM Jubb et al.
JOURNAL OF PATHOLOGY (2003)
Clinical significance of vascular endothelial growth factor expression and neovascularization in colorectal carcinoma
S Zheng et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2003)
The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression
V Hanrahan et al.
JOURNAL OF PATHOLOGY (2003)
Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis
JA Joyce et al.
CANCER CELL (2003)
Role of biological markers in the clinical outcome of colon cancer
O Nanni et al.
BRITISH JOURNAL OF CANCER (2002)
Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis
C Mailhos et al.
DIFFERENTIATION (2001)
Tissue microarray (TMA) technology:: miniaturized pathology archives for high-throughput in situ studies
L Bubendorf et al.
JOURNAL OF PATHOLOGY (2001)
The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
KL Talks et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)