Journal
BRITISH JOURNAL OF CANCER
Volume 99, Issue 3, Pages 392-397Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6604483
Keywords
drug targeting; nanomedicines; liposomes; polymers
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Drug targeting systems are nanometre-sized carrier materials designed for improving the biodistribution of systemically applied ( chemo) therapeutics. Various different tumour-targeted nanomedicines have been evaluated over the years, and clear evidence is currently available for substantial improvement of the therapeutic index of anticancer agents. Here, we briefly summarise the most important targeting systems and strategies, and discuss recent advances and future directions in the development of tumour-targeted nanomedicines.
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