Journal
BRITISH JOURNAL OF CANCER
Volume 99, Issue 7, Pages 1161-1164Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6604639
Keywords
hormones; birth weight; maternal age; parity; smoking
Categories
Funding
- Divisions of Cancer Epidemiology and Genetics and Cancer Control and Population Sciences
- National Cancer Institute
- National Institutes of Health
- US Department of Health and Human Services
- HD [39223]
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In uncomplicated pregnancies, first trimester androgen, oestrogen and prolactin concentrations were higher in nulliparous (n = 160) than parous (n = 260) mothers. Androgens and estrogens were higher in younger than older mothers. These data are consistent with elevated hormone concentrations mediating the breast cancer protection from a first pregnancy and pregnancies occurring at younger ages.
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