Journal
BRITISH JOURNAL OF ANAESTHESIA
Volume 111, Issue 1, Pages 64-72Publisher
ELSEVIER SCI LTD
DOI: 10.1093/bja/aet174
Keywords
chronic pain; neuroimaging; magnetic resonance imaging; functional
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Funding
- National Institute of Health Research Oxford Biomedical Research Centre
- Wellcome Trust
- Medical Research Council of Great Britain and Northern Ireland
- Medical Research Council [G0700399] Funding Source: researchfish
- MRC [G0601340, G0700399] Funding Source: UKRI
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Chronic pain is a state of physical suffering strongly associated with feelings of anxiety, depression and despair. Disease pathophysiology, psychological state, and social milieu can influence chronic pain, but can be difficult to diagnose based solely on clinical presentation. Here, we review brain neuroimaging research that is shaping our understanding of pain mechanisms, and consider how such knowledge might lead to useful diagnostic tools for the management of persistent pain in individual patients.
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