3.9 Article

NEW DEVELOPMENTS IN THE MEDICINAL CHEMISTRY OF CARBORANES

Journal

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
Volume 75, Issue 9, Pages 995-1022

Publisher

INST ORGANIC CHEM AND BIOCHEM
DOI: 10.1135/cccc2010050

Keywords

Carboranes; Metallacarboranes; Medicinal chemistry; Nanoparticles; Dendrimers; Porphyrins; Carbohydrates

Funding

  1. National Science Foundation [CHE-0906179]
  2. Robert A. Welch Foundation [N-1322]
  3. Alexander von Humboldt Foundation
  4. NIU

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The advancements in the synthetic chemistry of carboranes and metallacarboranes have given rise to diversified uses in medicinal chemistry, resulting in many new medical applications. An overview of the medicinal chemistry of carboranes is presented emphasizing the use of nanoparticles, dendrimers, porphyrins and carbohydrates as boron carriers. A review with 80 references.

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