Journal
GUT MICROBES
Volume 1, Issue 4, Pages 234-242Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/gmic.1.4.12706
Keywords
Clostridium difficile; infection; CDI; CDAD; hypervirulent; spore; infection control; pathogenesis
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Funding
- US Department of Veterans Affairs
- University of Arizona
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Clostridium difficile infection (CDI) is the primary cause of antibiotic-associated diarrhea and is a significant nosocomial disease. In the past ten years, variant toxin-producing strains of C. difficile have emerged, that have been associated with severe disease as well as outbreaks worldwide. This review summarizes current information on C. difficile pathogenesis and disease, and highlights interventions used to combat single and recurrent episodes of CDI.
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