Journal
TRANSCRIPTION-AUSTIN
Volume 1, Issue 1, Pages 13-16Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/trns.1.1.11984
Keywords
transcription; gene regulation; nuclear receptor; chromatin; stochastic modeling
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Funding
- University of Luxembourg
- Academy of Finland
- Juselius Foundation
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Research of the past decade showed that transcriptional regulation could be a highly dynamic and cyclical process. Many transcription factors and their co-regulators cyclically associate with a periodicity of 30-75 min with regulatory chromatin regions resulting in dynamically changing chromatin marks and cyclical activities of RNA polymerase II in mRNA synthesis.
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