4.1 Article

Action of mouthwashes on Staphylococcus spp. isolated in the saliva of community and hospitalized individuals

Journal

BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 45, Issue 3, Pages 551-557

Publisher

UNIV SAO PAULO, CONJUNTO QUIMICAS
DOI: 10.1590/S1984-82502009000300021

Keywords

Oral health; Staphylococcus spp.; Mouthwashes; Oral hygiene

Funding

  1. FAPESP

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The use of mouthwashes in critical patients has been a source of concern for health professionals due to the diverse range of products, causing uncertainty about which is the most indicated. This study aimed to assess the susceptibility of Staphylococcus spp. isolated in the saliva of individuals from the community and patients in Intensive Care Units (ICU) as to antiseptic mouthwashes. The following oral antiseptics were assessed cetylpyridimum chloride solution, Listerine (R) and Neen (R) Calcium algmate swab was used for saliva collection to isolate Staphylococcus spp. Microbiological processing involved growth, isolation, strain identification and determination of MID (maximum inhibitory dilution). MID was considered the greatest dilution that completely inhibited the strains. The products efficacy was analyzed by a two-factor ANOVA repeated measures and by Bonferrom adjustments in multiple comparisons, considering a significance level of alpha = 0.05. In total, 80 strains of Staphylococcus spp. were isolated. 40 from ICU patients and 40 from community individuals MID results revealed that cetylpyridinium chloride solution presented better results in comparison to other products, that is, 39 (97.5%) strains from hospital patients with MID 1:128, and 37 (9205%) of individuals from the community had MID 16 Neen (R) inhibited all strains in both groups at a dilution form 1.2 to 1.4 Listerine (R) presented the worst MID results. 65% of the strains from individuals from the community and 10% of hospital strains were not inhibited at a dilution of 1.2.

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