4.2 Article

EVALUATION OF A LIPOPEPTIDE BIOSURFACTANT FROM BACILLUS NATTO TK-1 AS A POTENTIAL SOURCE OF ANTI-ADHESIVE, ANTIMICROBIAL AND ANTITUMOR ACTIVITIES

Journal

BRAZILIAN JOURNAL OF MICROBIOLOGY
Volume 40, Issue 2, Pages 373-379

Publisher

SPRINGER
DOI: 10.1590/S1517-83822009000200030

Keywords

Biosurfactant; anti-adhesive; antimicrobial activity; antitumor

Categories

Funding

  1. National Natural Science Foundation of China [20676103]

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A lipopeptide biosurfactant produced by Bacillus natto TK-1 has a strong surface activity. The biosurfactant was found to be an anti-adhesive agent against several bacterial strains, and also showed a broad spectrum of antimicrobial activity. The biosurfactant induced a significant reduction in tumor cells viability in a dose-dependent manner.

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