Related references
Note: Only part of the references are listed.NOTCH1 mutation can be an early, prenatal genetic event in T-ALL
Minenori Eguchi-Ishimae et al.
BLOOD (2008)
NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis
Joachim R. Goethert et al.
BLOOD (2007)
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
Teresa Palomero et al.
NATURE MEDICINE (2007)
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
Richard S. Maser et al.
NATURE (2007)
Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling
Huw D. Lewis et al.
CHEMISTRY & BIOLOGY (2007)
Signaling pathways in cancer and embryonic stem cells
Oliver Dreesen et al.
STEM CELL REVIEWS (2007)
ERK5 activates NF-κB in leukemic T cells and is essential for their growth in vivo
Johan Garaude et al.
JOURNAL OF IMMUNOLOGY (2006)
Molecular and functional evidence for activity of murine IL-7 on human lymphocytes
Joao T. Barata et al.
EXPERIMENTAL HEMATOLOGY (2006)
Resveratrol-induced apoptosis is enhanced in acute lymphoblastic leukemia cells by modulation of the mitochondrial permeability transition pore
Susan J. Zunino et al.
CANCER LETTERS (2006)
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
Andrew P. Weng et al.
GENES & DEVELOPMENT (2006)
MAPK signalling: ERK5 versus ERK1/2
Satoko Nishimoto et al.
EMBO REPORTS (2006)
p38-MAP kinase activation followed by BIM induction is essential for glucocorticoid-induced apoptosis in lymphoblastic leukemia cells
Jianghua Lu et al.
FEBS LETTERS (2006)
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
Omer H. Yilmaz et al.
NATURE (2006)
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
Jiwang Zhang et al.
NATURE (2006)
Survival signaling by Notch1: Mammalian target of rapamycin (mTOR)-dependent inhibition of p53
Sathish Kumar Mungamuri et al.
CANCER RESEARCH (2006)
Cross talk among Notch3, pre-TCR, and Tall in T-cell development and leukemogenesis
C Talora et al.
BLOOD (2006)
Recent insights into the role of Notch signaling in tumorigenesis
KG Leong et al.
BLOOD (2006)
JAW/STAT signal transduction: Regulators and implication in hematological malignancies
L Valentino et al.
BIOCHEMICAL PHARMACOLOGY (2006)
Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells
R Avellino et al.
BLOOD (2005)
Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32)
K De Keersmaecker et al.
BLOOD (2005)
Interleukin-7 in T-cell acute lymphoblastic leukemia: An extrinsic factor supporting leukemogenesis?
JT Barata et al.
LEUKEMIA & LYMPHOMA (2005)
IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL
JT Barata et al.
BLOOD (2004)
Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells
JT Barata et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Loss of Smad3 in acute T-cell lymphoblastic leukemia
LA Wolfraim et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Inhibition of phosphatidylinositol 3′-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway
S Uddin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
SCL: From the origin of hematopoiesis to stem cells and leukemia
E Lecuyer et al.
EXPERIMENTAL HEMATOLOGY (2004)
SOCS1 and SHP1 hypermethylation in multiple myeloma:: implications for epigenetic activation of the Jak/STAT pathway
CS Chim et al.
BLOOD (2004)
T cell acute lymphoblastic leukemia/lymphoma: a human cancer commonly associated with aberrant NOTCH1 signaling
WS Pear et al.
CURRENT OPINION IN HEMATOLOGY (2004)
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
PP Roux et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2004)
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng et al.
SCIENCE (2004)
Notch and T cell malignancy
PA Zweidler-McKay et al.
SEMINARS IN CANCER BIOLOGY (2004)
Smad-dependent and Smad-independent pathways in TGF-β family signalling
R Derynck et al.
NATURE (2003)
Mechanisms of TGF-β signaling from cell membrane to the nucleus
YG Shi et al.
CELL (2003)
Specificity of arachidonic acid-induced inhibition of growth and activation of c-jun kinases and p38 mitogen-activated protein kinase in hematopoietic cells
MT Rizzo et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2002)
A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer
XQ Yan et al.
BLOOD (2001)
Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27kip1
JT Barata et al.
BLOOD (2001)
Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation
J Frantsve et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts:: Role of activated STAT3 signaling
D Sinibaldi et al.
ONCOGENE (2000)
Constitutive activation of NF-κB and T-cell leukemia/lymphoma in Notch3 transgenic mice
D Bellavia et al.
EMBO JOURNAL (2000)
Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice
CD Hoemann et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Transcription factor NF-kappa B is constitutively activated in acute lymphoblastic leukemia cells
U Kordes et al.
LEUKEMIA (2000)
Share Paper
