Journal
BRAIN TOPOGRAPHY
Volume 25, Issue 2, Pages 125-128Publisher
SPRINGER
DOI: 10.1007/s10548-012-0219-0
Keywords
Amygdala; fMRI; 7 Tesla; Fear; Face perception
Categories
Funding
- Centre d'Imagerie BioMedicale (CIBM) of the University of Lausanne (UNIL)
- Swiss Federal Institute of Technology Lausanne (EPFL)
- University of Geneva (UniGe)
- Centre Hospitalier Universitaire Vaudois (CHUV)
- Hopitaux Universitaires de Geneve (HUG)
- Leenaards Foundation
- Jeantet Foundation
- [FNS PP00P3_130191]
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The amygdalae are involved in the perception of emotions such as happiness, anger and fear. Because of their proximity to the sinuses, the image signal intensity in T2* weighted fMRI data is often affected by signal loss due to through-slice dephasing, especially at high field strength. In this study, the feasibility of fMRI in the amygdalae at 7 Tesla was investigated. A paradigm based on the presentation of fearful faces was used for stimulation. Previously, opposite effects have been found for presentation of averted and direct gaze fearful faces. Here, we show that (1) sufficiently high temporal SNR values are reached in the amygdalae for detection of small BOLD signal changes and (2) that the BOLD signal in the amygdalae for presentation of a direct or averted gaze in a fearful face depends on stimulus duration.
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