Journal
ANALYTICAL CHEMISTRY
Volume 88, Issue 1, Pages 592-595Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.5b03636
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Funding
- National Natural Science Foundation of China [21402130]
- National Program on Key Basic Research Project [2013CB734000]
- Program of New Century Excellent Talents in University [NCET-11-0306]
- Shandong Natural Science Foundation [JQ201019]
- Fundamental Research Funds of Shandong University [2014JC008]
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Considering that hydrogen sulfide (H2S) is an endogenous signaling molecule involved in numerous biological processes, a method for monitoring H2S as a powerful tool for investigating its complicated functions and mechanisms is urgently demanded. Herein, a bioluminescent turn-on probe was reported based on caged strategy for the detection of H2S in vitro and in vivo. This probe will help us understand the intricate contribution of H2S to a variety of physiological and pathological processes.
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