Journal
BRAIN RESEARCH
Volume 1293, Issue -, Pages 108-113Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.brainres.2009.03.062
Keywords
Restraint stress; Sex differences; Neuronal plasticity; Stress recovery; Depression; PTSD
Categories
Funding
- NIMH NIH HHS [F32 MH075506-03, F32 MH075506] Funding Source: Medline
Ask authors/readers for more resources
The medial prefrontal cortex (mPFC) has been implicated as a site of dysfunction and abnormal morphology in major depressive disorder and post-traumatic stress disorder, two illnesses that can be brought on by exposure to stress. In animal models, stress has long been shown to induce impairments in tasks known to be mediated by the mPFC, and recent work has demonstrated that chronic stress can lead to morphological changes in mPFC pyramidal cells. This review explores the current literature on stress-induced dendritic remodeling in the mPFC, with particular focus on new findings that illuminate modulators of these effects. (C) 2009 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available