Journal
BRAIN & DEVELOPMENT
Volume 36, Issue 1, Pages 70-73Publisher
ELSEVIER
DOI: 10.1016/j.braindev.2012.12.006
Keywords
Parechovirus; Enterovirus; Neonatal encephalitis; Magnetic resonance imaging; RT-PCR
Categories
Funding
- RC [80622]
- Ricerca Finalizzata Mondino (convenzione) [68]
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Human parechoviruses (HPeVs) are a new family of neurotropic viruses that cause central nervous system (CNS) infections similar to enterovirus (EVs) meningoencephalitis in the neonatal period, resulting in white matter lesions that can be visualized with cranial ultrasonography and magnetic resonance imaging, and correlated to a large spectrum of neurological outcomes. HPeV should be suspected in neonates with signs and symptoms of sepsis-like illness or CNS disease. We report a case of neonatal HPeV encephalitis, diagnosed on the basis of clinical and radiological findings and HPeV RT-PCR, with a good neurological outcome. (C) 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.
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