Related references
Note: Only part of the references are listed.A phenotypically restricted set of primary afferent nerve fibers innervate the bone versus skin: Therapeutic opportunity for treating skeletal pain
Juan Miguel Jimenez-Andrade et al.
BONE (2010)
AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist
Joel R. Gever et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Endogenous Purinergic Control of Bladder Activity via Presynaptic P2X3 and P2X2/3 Receptors in the Spinal Cord
Timothy K. Y. Kaan et al.
JOURNAL OF NEUROSCIENCE (2010)
P2X7-Dependent Release of Interleukin-1β and Nociception in the Spinal Cord following Lipopolysaccharide
Anna K. Clark et al.
JOURNAL OF NEUROSCIENCE (2010)
Cancer-related pain: a pan-European survey of prevalence, treatment, and patient attitudes
H. Breivik et al.
ANNALS OF ONCOLOGY (2009)
Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X3/P2X2/3 antagonist for the treatment of pain
Alam Jahangir et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X3/P2X2/3 antagonist for the treatment of pain
David S. Carter et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
P2X receptors in sensory neurons co-cultured with cancer cells exhibit a decrease in opioid sensitivity
I. Chizhmakov et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
The management of cancer-related breakthrough pain: Recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland
Andrew N. Davies et al.
EUROPEAN JOURNAL OF PAIN (2009)
Rapid isolation and culture of primary microglia from adult mouse spinal cord
Ping K. Yip et al.
JOURNAL OF NEUROSCIENCE METHODS (2009)
Translational medicine: cancer pain mechanisms and management
A. Delaney et al.
BRITISH JOURNAL OF ANAESTHESIA (2008)
A Decrease in Anandamide Signaling Contributes to the Maintenance of Cutaneous Mechanical Hyperalgesia in a Model of Bone Cancer Pain
Iryna A. Khasabova et al.
JOURNAL OF NEUROSCIENCE (2008)
Tumor-evoked hyperalgesia and sensitization of nociceptive dorsal horn neurons in a murine model of cancer pain
Sergey G. Khasabov et al.
BRAIN RESEARCH (2007)
Chemical interactions between fibrosarcoma cancer cells and sensory neurons contribute to cancer pain
Iryna A. Khasabova et al.
JOURNAL OF NEUROSCIENCE (2007)
Neutralization of nerve growth factor induces plasticity of ATP-sensitive P2X3 receptors of nociceptive trigeminal ganglion neurons
Marianna D'Arco et al.
JOURNAL OF NEUROSCIENCE (2007)
Long-term potentiation of neuronal excitation by neuron-glia interactions in the rat spinal dorsal horn
Hiroshi Ikeda et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Acidic microenvironment created by osteoclasts causes bone pain associated with tumor colonization
Maho Nagae et al.
JOURNAL OF BONE AND MINERAL METABOLISM (2007)
The ERK 1 and 2 pathway in the nervous system: From basic aspects to possible clinical applications in pain and visceral dysfunction
Celia D. Cruz et al.
CURRENT NEUROPHARMACOLOGY (2007)
Investigation into the role of P2X3/P2X2/3 receptors in neuropathic pain following chronic constriction injury in the rat:: an electrophysiological study
Caroline J. Sharp et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Cancer pain and its impact on diagnosis, survival and quality of life
Patrick W. Mantyh
NATURE REVIEWS NEUROSCIENCE (2006)
Mechanical allodynia and thermal hyperalgesia induced by experimental squamous cell carcinoma of the lower gingiva in rats
Kenjiro Nagamine et al.
JOURNAL OF PAIN (2006)
Pharmacology of P2X channels
Joel R. Gever et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2006)
The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint
Daisuke Seino et al.
PAIN (2006)
Effects of the RANKL inhibitor, osteoprotegerin, on the pain and histopathology of bone cancer in rats
Martine P. Roudier et al.
CLINICAL & EXPERIMENTAL METASTASIS (2006)
Retinoic acid receptor β2 promotes functional regeneration of sensory axons in the spinal cord
LF Wong et al.
NATURE NEUROSCIENCE (2006)
Purinergic P2 receptors as targets for novel analgesics
Geoffrey Burnstock
PHARMACOLOGY & THERAPEUTICS (2006)
Efficacy of chronic morphine in a rat model of cancer-induced bone pain: Behavior and in dorsal horn pathophysiology
CE Urch et al.
JOURNAL OF PAIN (2005)
Analgesic efficacy of bradykinin B1 antagonists in a murine bone cancer pain model
MA Sevcik et al.
JOURNAL OF PAIN (2005)
A blocking antibody to nerve growth factor attenuates skeletal pain induced by prostate tumor cells growing in bone
KG Halvorson et al.
CANCER RESEARCH (2005)
Parallel pain pathways arise from subpopulation of primary afferent nociceptor
JM Braz et al.
NEURON (2005)
P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP
DA Cockayne et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Re-organization of P2X3 receptor localization on epidermal nerve fibers in a murine model of cancer pain
LS Gilchrist et al.
BRAIN RESEARCH (2005)
Anti-NGF therapy profoundly reduces bone cancer pain and the accompanying increase in markers of peripheral and central sensitization
MA Sevcik et al.
PAIN (2005)
Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain
JR Ghilardi et al.
JOURNAL OF NEUROSCIENCE (2005)
MAPK activation in nociceptive neurons and pain hypersensitivity
K Obata et al.
LIFE SCIENCES (2004)
Contribution of sensitized P2X receptors in inflamed tissue to the mechanical hypersensitivity revealed by phosphorylated ERK in DRG neurons
Y Dai et al.
PAIN (2004)
siRNA relieves chronic neuropathic pain
G Dorn et al.
NUCLEIC ACIDS RESEARCH (2004)
Bone cancer pain:: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis
MA Sevcik et al.
PAIN (2004)
Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat
A Fox et al.
PAIN (2004)
A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats
G Wu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Endothelin and the tumorigenic component of bone cancer pain
CM Peters et al.
NEUROSCIENCE (2004)
Cancer pain
E Bruera et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)
In vivo single unit extracellular recordings from spinal cord neurones of rats
CE Urch et al.
BRAIN RESEARCH PROTOCOLS (2003)
Alterations in dorsal horn neurones in a rat model of cancer-induced bone pain
CE Urch et al.
PAIN (2003)
Effects of A-317491, a novel and selective P2X(3)/P2X(2/3) receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration
S McGaraughty et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
A-317491, a novel potent and selective nonnucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat
MF Jarvis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Disease modifying and anti-nociceptive effects of the bisphosphonate, zoledronic acid in a model of bone cancer pain
K Walker et al.
PAIN (2002)
Analgesic profile of intrathecal P2X3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
P Honore et al.
PAIN (2002)
Metastasis to bone: Causes, consequences and therapeutic opportunities
GR Mundy
NATURE REVIEWS CANCER (2002)
P2X receptors in peripheral neurons
PM Dunn et al.
PROGRESS IN NEUROBIOLOGY (2001)
Nerve growth factor induces P2X3 expression in sensory neurons
MS Ramer et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice
DA Cockayne et al.
NATURE (2000)
Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors
V Souslova et al.
NATURE (2000)
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord
P Honore et al.
NATURE MEDICINE (2000)