Journal
BONE
Volume 43, Issue 3, Pages 414-417Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.bone.2008.05.005
Keywords
sex steroids; osteoporosis; skeletal physiological; bone turnover
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Funding
- NIAMS NIH HHS [R01 AR027065-27, R01 AR027065] Funding Source: Medline
- NIA NIH HHS [P01 AG004875, P01 AG004875-25, R01 AG028936, R01 AG028936-03] Funding Source: Medline
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Findings from estrogen-resistant and aromatase-deficient men have provided important insights into the role of estrogen in the male skeleton during growth. importantly, as reported elsewhere in this issue, these data also suggested dose-response relationships between estrogen and bone turnover. In addition, studies in these unusual patients have stimulated research on defining the role of estrogen in regulating bone metabolism in normal adult and aging men, providing further insights into estrogen regulation of bone metabolism not only in men, but also in women. (C) 2008 Elsevier Inc. All rights reserved.
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