Multi-sensory and sensorimotor foundation of bodily self-consciousness - an interdisciplinary approach

Scientific investigations on the nature of the self have so far focused on high-level mechanisms. Recent evidence, however, suggests that low-level bottom-up mechanisms of multi-sensory integration play a fundamental role in encoding specific components of bodily self-consciousness, such as self-location and first-person perspective (Blanke and Metzinger, 2009). Self-location and first-person perspective are abnormal in neurological patients suffering from out-of-body experiences (Blanke et al., 2004), and can be manipulated experimentally in healthy subjects by imposing multi-sensory conflicts (Lenggenhager 2009). Activity of the temporo-parietal junction (TPJ) reflects experimentally induced changes in self-location and first-person perspective (lonta et al., 2011), and dysfunctions in TPJ are causally associated with out-of-body experiences (Blanke et al., 2002). We argue that TPJ is one of the key areas for multi-sensory integration of bodily self-consciousness, that its levels of activity reflect the experience of the conscious I as embodied and localized within bodily space, and that these mechanisms can be systematically investigated using state of the art technologies such as robotics, virtual reality, and non-invasive neuroimaging.