Journal
PLANT SIGNALING & BEHAVIOR
Volume 7, Issue 12, Pages 1561-1565Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/psb.22460
Keywords
MORC; GHKL ATPase; DNA methylation; histone modification; H3K27 monomethylation (H3K27me); RNA directed DNA methylation; Arabidopsis
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Funding
- Austrian Academy of Sciences
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Two recent studies in Arabidopsis implicated MORC proteins, which contain a GHKL AT Pase domain, in transcriptional gene silencing. Here, these studies are compared and contrasted to discuss the roles of MORC proteins in epigenetic regulation. Although MORC proteins are likely to catalyze changes in chromatin structure in response to epigenetic signals, their precise mode of action and target site-specificity still remain unclear.
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