4.2 Article

The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Functional and binding kinetic studies make a distinction between OX1 and OX2 orexin receptor antagonists

Stefania Faedo et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2012)

Article Neurosciences

Pharmacological characterization of MK-6096-A dual orexin receptor antagonist for insomnia

Christopher J. Winrow et al.

NEUROPHARMACOLOGY (2012)

Article Clinical Neurology

Insomnia Pharmacotherapy

Timothy Roehrs et al.

NEUROTHERAPEUTICS (2012)

Article Genetics & Heredity

Promotion of Sleep by Suvorexant--A Novel Dual Orexin Receptor Antagonist

Christopher J. Winrow et al.

JOURNAL OF NEUROGENETICS (2011)

Article Clinical Neurology

Sex differences and the effect of gaboxadol and zolpidem on EEG power spectra in NREM and REM sleep

D. J. Dijk et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2010)

Article Pharmacology & Pharmacy

Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat

Christine Dugovic et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)

Review Neurosciences

The Role of Imaging in Proof of Concept for CNS Drug Discovery and Development

Dean F. Wong et al.

NEUROPSYCHOPHARMACOLOGY (2009)

Article Biochemistry & Molecular Biology

Promotion of sleep by targeting the orexin system in rats, dogs and humans

Catherine Brisbare-Roch et al.

NATURE MEDICINE (2007)

Article Multidisciplinary Sciences

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice

M Mieda et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Endocrinology & Metabolism

Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity

PJF Martins et al.

REGULATORY PEPTIDES (2004)

Article Clinical Neurology

Increased CSF hypocretin-1 (orexin-A) in restless legs syndrome

RP Allen et al.

NEUROLOGY (2002)

Review Neurosciences

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

JT Willie et al.

ANNUAL REVIEW OF NEUROSCIENCE (2001)

Article Neurosciences

The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats

DC Piper et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2000)

Article Medicine, General & Internal

Hypocretin (orexin) deficiency in human narcolepsy

S Nishino et al.

LANCET (2000)