Journal
JOURNAL OF THYROID RESEARCH
Volume 2012, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2012/569147
Keywords
-
Categories
Funding
- Portuguese Science Foundation (FCT/FEDER) [POCI/SAUESP/58757/2004]
- FCT [SFRH/BPD/51057/2010]
- Fundação para a Ciência e a Tecnologia [POCI/SAU-ESP/58757/2004] Funding Source: FCT
Ask authors/readers for more resources
Thyroid hormones are crucial during development and in the adult brain. Of interest, fluctuations in the levels of thyroid hormones at various times during development and throughout life can impact on psychiatric disease manifestation and response to treatment. Here we review research on thyroid function assessment in schizophrenia, relating interrelations between the pituitary-thyroid axis and major neurosignaling systems involved in schizophrenia's pathophysiology. These include the serotonergic, dopami-nergic, glutamatergic, and GABAergic networks, as well as myelination and inflammatory processes. The available evidence supports that thyroid hormones deregulation is a common feature in schizophrenia and that the implications of thyroid hormones homeostasis in the fine-tuning of crucial brain networks warrants further research.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available