Journal
PLANT SIGNALING & BEHAVIOR
Volume 8, Issue 8, Pages -Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/psb.25206
Keywords
transposable element; transposon; RNA-directed DNA Methylation; small interfering RNA; epigenetic; silencing; DNA methylation; RNAi
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Funding
- U.S. National Science Foundation [MCB1020499]
- Direct For Biological Sciences [1020499] Funding Source: National Science Foundation
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The activity of transposable elements is epigenetically suppressed by both transcriptional and post-transcriptional mechanisms. We recently identified a direct connection between the small RNA-mediated post-transcriptional mRNA degradation of actively transcribing transposable elements and the de novo methylation of transposable element DNA, providing a mechanistic link between these two established pathways of transposable element silencing. Here we provide a model for the initiation, establishment and epigenetic maintenance of transposable element silencing that incorporates recent data in this rapidly emerging field.
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