Journal
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
Volume 6, Issue -, Pages 453-464Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IJGM.S29977
Keywords
rhinosinusitis; chronic; nasal polyps; therapy; sinus
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This review describes the epidemiology and various treatments in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Evidence for short-term use of systemic corticosteroids has been shown to be favorable in CRSwNP, but still limited in CRSsNP. Topical corticosteroids improve symptom scores in both CRS subgroups. The role of microbes in CRS is still controversial. Culture-directed antibiotics are recommended for CRSsNP with exacerbation. Long-term use of low dosage antibiotics is recommended for CRSsNP for their anti-inflammatory effects. Other emerging treatment options are also discussed.
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