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t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature

Journal

CASE REPORTS IN HEMATOLOGY
Volume 2013, Issue -, Pages -

Publisher

HINDAWI LTD
DOI: 10.1155/2013/563291

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Funding

  1. Carolyn Perot Rathjen Chair in Pediatrics, Nashville, TN, USA

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Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia ( ALL) have been associated with a poor prognosis. There are several case reports in the literature describing t(17;19) in children with ALL.. is translocation has been associated with hypercalcemia, coagulopathy, and poor outcome. We present three cases of ALL with t(17;19) treated at our institution and review the outcome of children reported in the medical literature.

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