3.8 Article

Decoding human gene expression signatures in the brain

Journal

TRANSCRIPTION-AUSTIN
Volume 4, Issue 3, Pages 102-108

Publisher

TAYLOR & FRANCIS INC
DOI: 10.4161/trns.24885

Keywords

gene expression; genomics; coexpression; brain; nervous system; evolution

Ask authors/readers for more resources

The evolution of higher cognitive functions in humans is thought to be due, at least in part, to the molecular evolution of gene expression patterns specific to the human brain. In this article, we explore recent and past findings using comparative genomics in human and non-human primate brain to identify these novel human patterns. We suggest additional directions and lines of experimentation that should be taken to improve our understanding of these changes on the human lineage. Finally, we attempt to put into context these genomic changes with biological phenotypes and diseases in humans.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

3.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available