4.7 Article

HemaSpot, a Novel Blood Storage Device for HIV-1 Drug Resistance Testing

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 54, Issue 1, Pages 223-225

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.02853-15

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Funding

  1. HHS \ NIH \ National Institute of Allergy and Infectious Diseases (NIAID) [P30AI042853, R01AI66922, K23AI096923, T32DA13911]
  2. Spot On Sciences

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HemaSpot, a novel dried-blood storage filter device, was used for HIV-1 pol resistance testing in 30 fresh United States blood samples and 54 previously frozen Kenyan blood samples. Genotyping succeeded in 79% and 58% of samples, respectively, improved with shorter storage and higher viral load, and had good (86%) resistance mutation concordance to plasma.

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