4.7 Article

Recurrence of Disseminated Mycobacterium avium Complex Disease in a Patient with Anti-Gamma Interferon Autoantibodies by Reinfection

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 53, Issue 4, Pages 1436-1438

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.03339-14

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Funding

  1. Japan Society of the Promotion of Science KAKENHI [26860772]
  2. Ohyama Health Foundation
  3. Grants-in-Aid for Scientific Research [26860772, 25461520, 13J07208, 25461507] Funding Source: KAKEN

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We report a case of recurrent disseminated Mycobacterium avium complex (DMAC) disease with anti-gamma interferon auto-antibodies. To our knowledge, this is the first reported case caused by reinfection with a separate isolate of M. avium. DMAC disease activity was monitored using serum IgG antibody titers against lipid antigens extracted from a MAC strain.

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