Journal
PLANT SCIENCE TODAY
Volume 1, Issue 3, Pages 114-120Publisher
HORIZON E-PUBLISHING GROUP
DOI: 10.14719/pst.2014.1.3.41
Keywords
amaryllidaceae alkaloid; plant secondary metabolism; galanthamine biosynthesis; natural products; systems biology
Categories
Funding
- Natural Sciences and Engineering Research Council of Canada
- Universite du Quebec a Trois-Rivieres [Fonds Institutionnel de Recherche]
Ask authors/readers for more resources
Amaryllidaceae alkaloids (AAs) are a structurally diverse group of plant specialized metabolites with powerful biological activities. The medicinal properties of many AAs have been identified including the antitumor agent narciclasine and galanthamine, used for Alzheimer's disease. Tracer studies have led to proposed pathways but AA biosynthesis remains molecularly uncharacterized. The use of systems biology-based approaches could lead to the unraveling of AA metabolic pathways. The elucidation of AA biosynthesis will provide necessary tools required to enhance AA production in plants as well as the development of microbial production platforms as an alternative to plants as a commercial source of valuable AAs.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available