Journal
TRANSCRIPTION-AUSTIN
Volume 5, Issue 3, Pages -Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/trns.28658
Keywords
chromatin loops; enhancer; promoter; chromatin contact; multigene complex; gene regulation; transcription; lncRNA; eRNA; topologically associating domain
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Funding
- Council for Industrial and Scientific Research (CSIR, South Africa) [PG-V2KYP07]
- Emerging Research Area Program of The Department of Science and Technology (DST, South Africa)
- Fundacao para a Ciencia e a Tecnologia (FCT, Portugal) [PTDC/SAUGMG/115652/2009]
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Recent functional studies have unveiled the significant role chromatin topology plays in gene regulation. Several lines of evidence suggest genes access necessary factors for transcription by forming chromatin loops. A clearer picture of the players involved in chromatin organization, including lncRNA, is emerging.
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